百科

(2R,6S)-6-Methyl-2-{(R)-3-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4,5-dihydro-isoxazol-5-yl}-7-triisopropylsilanyloxy-heptan-2-ol

(2R,6S)-6-Methyl-2-{(R)-3-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4,5-dihydro-isoxazol-5-yl}-7-triisopropylsilanyloxy-heptan-2-ol

CAS号：342607-04-9

英文名：(2R,6S)-6-Methyl-2-{(R)-3-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4,5-dihydro-isoxazol-5-yl}-7-triisopropylsilanyloxy-heptan-2-ol

分子式：C27H48N2O3SSi

分子量：508.832

合成路线

1-{3-[1-methyl-(2E)-(2-methyl-thiazol-4-yl)-vinyl]-4,(5R)-dihydro-isoxazol-5-yl}-ethanone

1-{3-[1-methyl-(2E)-(2-methyl-thiazol-4-yl)-vinyl]-4,(5R)-dihydro-isoxazol-5-yl}-ethanone

(S)-(4-methyl-5-((triisopropylsilyl)oxy)pentyl)magnesium bromide

(S)-(4-methyl-5-((triisopropylsilyl)oxy)pentyl)magnesium bromide

(2R,6S)-6-Methyl-2-{(R)-3-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4,5-dihydro-isoxazol-5-yl}-7-triisopropylsilanyloxy-heptan-2-ol

(2R,6S)-6-Methyl-2-{(R)-3-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4,5-dihydro-isoxazol-5-yl}-7-triisopropylsilanyloxy-heptan-2-ol

上游原料

(S)-(4-methyl-5-((triisopropylsilyl)oxy)pentyl)magnesium bromide 1-{3-[1-methyl-(2E)-(2-methyl-thiazol-4-yl)-vinyl]-4,(5R)-dihydro-isoxazol-5-yl}-ethanone

下游产品

(5R)-hydroxy-2,6,(10S)-trimethyl-1-(2-methyl-thiazol-4-yl)-(6R)-(triethyl-silanyloxy)-11-(triisopropyl-silanyloxy)-undec-(1E)-en-3-one