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(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

CAS号：346701-76-6

英文名：(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

分子式：C28H45BrO5Si

分子量：569.643

合成路线

(2R,3S)-5-bromo-2,3-epoxy-hex-5-enal

(2R,3S)-5-bromo-2,3-epoxy-hex-5-enal

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(4S)-4-benzyl-3-{(2S,3R)-3-hydroxy-5--[(4-methoxybenzyl)oxy]-2-methylpentanoyl}-1,3-oxazolidin-2-one

(4S)-4-benzyl-3-{(2S,3R)-3-hydroxy-5--[(4-methoxybenzyl)oxy]-2-methylpentanoyl}-1,3-oxazolidin-2-one

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(1S,4R)-1-[(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-4-[(R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-3-methylene-pentan-1-ol

(1S,4R)-1-[(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-4-[(R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-3-methylene-pentan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

[(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-methanol

[(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-methanol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

(3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptan-1-ol

上游原料

(2R,3S)-5-bromo-2,3-epoxy-hex-5-enal (1S,4R)-1-[(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-4-[(R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-3-methylene-pentan-1-ol (4S)-4-benzyl-3-{(2S,3R)-3-hydroxy-5--[(4-methoxybenzyl)oxy]-2-methylpentanoyl}-1,3-oxazolidin-2-one [(2S,3S)-3-(2-Bromo-allyl)-oxiranyl]-methanol

下游产品

(4R,7S,8R,9S)-11-bromo-7-(tert-butyldimethylsilanoxy)-8,9-epoxy-4-methyl-5-methylene-3-oxo-dodec-11-enoic acid methyl ester (3R,4R,7S)-7-[(2R,3S)-3-(2-Bromo-allyl)-oxiranyl]-7-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-5-methylene-heptanoic acid methyl ester