百科

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

CAS号：359795-90-7

英文名：(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

分子式：C20H36O5

分子量：356.497

合成路线

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-{(R)-3-[(tert-butyldimethylsilyl)oxymethyl]-1-pentyl}-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-{(R)-3-[(tert-butyldimethylsilyl)oxymethyl]-1-pentyl}-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(Z)-(2S,8R,9S,12R)-9-(tert-Butyl-dimethyl-silanyloxy)-12-(tert-butyl-dimethyl-silanyloxymethyl)-2-((4S,6R)-2,2-di-tert-butyl-6-methyl-[1,3,2]dioxasilinan-4-yl)-5-(N',N'-dimethyl-hydrazino)-8-methyl-tetradec-5-en-7-one

(Z)-(2S,8R,9S,12R)-9-(tert-Butyl-dimethyl-silanyloxy)-12-(tert-butyl-dimethyl-silanyloxymethyl)-2-((4S,6R)-2,2-di-tert-butyl-6-methyl-[1,3,2]dioxasilinan-4-yl)-5-(N',N'-dimethyl-hydrazino)-8-methyl-tetradec-5-en-7-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2R,3S,6R)-3-[(tert-butyldimethylsilyl)oxy]-6-[(tert-butyldimethylsilyl)oxymethyl]-2-methyloctanal

(2R,3S,6R)-3-[(tert-butyldimethylsilyl)oxy]-6-[(tert-butyldimethylsilyl)oxymethyl]-2-methyloctanal

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(R)-4-ethyl-5-<(tert-butyldimethylsilyl)oxy>pentanal

(R)-4-ethyl-5-<(tert-butyldimethylsilyl)oxy>pentanal

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-[(R)-3-hydroxymethyl-1-pentyl]-1,7-dioxaspiro[5.5]undecan-4-one

上游原料

(Z)-(2S,8R,9S,12R)-9-(tert-Butyl-dimethyl-silanyloxy)-12-(tert-butyl-dimethyl-silanyloxymethyl)-2-((4S,6R)-2,2-di-tert-butyl-6-methyl-[1,3,2]dioxasilinan-4-yl)-5-(N',N'-dimethyl-hydrazino)-8-methyl-tetradec-5-en-7-one (2S,3R,6R,8S,9S)-3,9-dimethyl-8-[(R)-2-hydroxy-1-propyl]-2-{(R)-3-[(tert-butyldimethylsilyl)oxymethyl]-1-pentyl}-1,7-dioxaspiro[5.5]undecan-4-one (R)-4-ethyl-5-<(tert-butyldimethylsilyl)oxy>pentanal (2R,3S,6R)-3-[(tert-butyldimethylsilyl)oxy]-6-[(tert-butyldimethylsilyl)oxymethyl]-2-methyloctanal

下游产品

(2S,3R,6R,8S,9S)-3,9-dimethyl-8-{(R)-2-[(tert-butyldimethylsilyl)oxy]-1-propyl}-2-{(R)-3-[(tert-butyldimethylsilyl)oxymethyl]-1-pentyl}-1,7-dioxaspiro[5.5]undecan-4-one