(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

CAS号：359818-74-9

英文名：(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

分子式：C17H23NO6

分子量：337.368

合成路线

(3aS,10S,11aR)-10-(((tert-butyldimethylsilyl)oxy)methyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(((tert-butyldimethylsilyl)oxy)methyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

((3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-3-yl)methanol

((3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-3-yl)methanol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

359818-64-7

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

2,2,2-trifluoro-1-((3R,3aR,9aS,12aS)-3-(hydroxymethyl)-4-methoxy-6,11,11-trimethyl-3,3a,9a,12a-tetrahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-8(9H)-yl)ethan-1-one

2,2,2-trifluoro-1-((3R,3aR,9aS,12aS)-3-(hydroxymethyl)-4-methoxy-6,11,11-trimethyl-3,3a,9a,12a-tetrahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-8(9H)-yl)ethan-1-one

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

ethyl (3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-8-((4-nitrophenyl)sulfonyl)-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocine-3-carboxylate

ethyl (3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-8-((4-nitrophenyl)sulfonyl)-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocine-3-carboxylate

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aS)-10-Hydroxymethyl-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol

(3aS,10S,11aS)-10-Hydroxymethyl-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(R)-1-((3aS,10S,11aS)-11-Hydroxy-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-10-yl)-ethane-1,2-diol

(R)-1-((3aS,10S,11aS)-11-Hydroxy-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-10-yl)-ethane-1,2-diol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aS)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol

(3aS,10S,11aS)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

Acetic acid (3aS,10S,11aS)-10-(tert-butyl-dimethyl-silanyloxymethyl)-11-hydroxy-9-methoxy-2,2,7-trimethyl-3a,10,11,11a-tetrahydro-4H-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-5-yl ester

Acetic acid (3aS,10S,11aS)-10-(tert-butyl-dimethyl-silanyloxymethyl)-11-hydroxy-9-methoxy-2,2,7-trimethyl-3a,10,11,11a-tetrahydro-4H-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-5-yl ester

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

(3aS,10S,11aR)-10-(hydroxymethyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol

上游原料

(3aS,10S,11aS)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol 2,2,2-trifluoro-1-((3R,3aR,9aS,12aS)-3-(hydroxymethyl)-4-methoxy-6,11,11-trimethyl-3,3a,9a,12a-tetrahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-8(9H)-yl)ethan-1-one ((3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocin-3-yl)methanol (3aS,10S,11aR)-10-(((tert-butyldimethylsilyl)oxy)methyl)-9-methoxy-2,2,7-trimethyl-3a,11a-dihydro-4H-5,11-epoxybenzo[b][1,3]dioxolo[4,5-f]azocin-11(10H)-ol (3aS,10S,11aS)-10-Hydroxymethyl-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-11-ol ethyl (3R,3aR,9aS,12aS)-4-methoxy-6,11,11-trimethyl-8-((4-nitrophenyl)sulfonyl)-3,3a,8,9,9a,12a-hexahydrobenzo[b][1,3]dioxolo[4,5-f]isoxazolo[4,3-d]azocine-3-carboxylate (R)-1-((3aS,10S,11aS)-11-Hydroxy-9-methoxy-2,2,7-trimethyl-3a,4,5,10,11,11a-hexahydro-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-10-yl)-ethane-1,2-diol Acetic acid (3aS,10S,11aS)-10-(tert-butyl-dimethyl-silanyloxymethyl)-11-hydroxy-9-methoxy-2,2,7-trimethyl-3a,10,11,11a-tetrahydro-4H-1,3-dioxa-5-aza-benzo[a]cyclopenta[e]cycloocten-5-yl ester

下游产品

(5R,6S,12bS)-12-methoxy-3,3,10-trimethyl-1,6,7,12b-tetrahydro-5H-4a,8-epoxybenzo[b][1,3]dioxino[5,4-d]azocine-5,6-diol (4aS,10aS,11aS)-5-methoxy-7-methyl-4,4a,10a,11a-tetrahydro-10H-9,11b-epoxybenzo[b][1,3]dioxino[5,4-d]oxireno[2,3-f]azocin-2-one (4aS,10aR,11aR)-5-methoxy-7-methyl-4,4a,10,10a,11,11a-hexahydro-9,11b-epoxyazirino[2,3-f]benzo[b][1,3]dioxino[5,4-d]azocin-2-one (4aS,10aS,11aS)-5-methoxy-2,2,7-trimethyl-4,4a,10a,11a-tetrahydro-10H-9,11b-epoxybenzo[b][1,3]dioxino[5,4-d]oxireno[2,3-f]azocine (5S,6R,12bS)-6-azido-12-methoxy-10-methyl-3-oxo-1,6,7,12b-tetrahydro-5H-4a,8-epoxybenzo[b][1,3]dioxino[5,4-d]azocin-5-yl methanesulfonate (5R,6S,12bS)-12-methoxy-3,3,10-trimethyl-6-((triethylsilyl)oxy)-1,6,7,12b-tetrahydro-5H-4a,8-epoxybenzo[b][1,3]dioxino[5,4-d]azocin-5-yl methanesulfonate