3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

CAS号：377777-94-1

英文名：3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

分子式：C51H46N4O9

分子量：858.932

合成路线

5-(2-Carboxy-ethyl)-2-methoxy-benzoic acid benzyl ester

5-(2-Carboxy-ethyl)-2-methoxy-benzoic acid benzyl ester

3-[2'-((S)-1-Amino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-[2'-((S)-1-Amino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

4-(2-Benzyloxy-phenyl)-3-[2'-((S)-1-tert-butoxycarbonylamino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-indole-1-carboxylic acid methyl ester

4-(2-Benzyloxy-phenyl)-3-[2'-((S)-1-tert-butoxycarbonylamino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(4-Methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester

3-(4-Methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(3-Formyl-4-methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester

3-(3-Formyl-4-methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

3-(2'-{(S)-1-[3-(3-Benzyloxycarbonyl-4-methoxy-phenyl)-propionylamino]-2-methyl-propyl}-[2,4']bioxazolyl-5-yl)-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester

上游原料

4-(2-Benzyloxy-phenyl)-3-[2'-((S)-1-tert-butoxycarbonylamino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-indole-1-carboxylic acid methyl ester 3-(4-Methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester 3-[2'-((S)-1-Amino-2-methyl-propyl)-[2,4']bioxazolyl-5-yl]-4-(2-benzyloxy-phenyl)-indole-1-carboxylic acid methyl ester 3-(3-Formyl-4-methoxy-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester 5-(2-Carboxy-ethyl)-2-methoxy-benzoic acid benzyl ester

下游产品

methyl (S,Z)-12-isopropyl-76-methoxy-6,10-dioxo-31H-5-oxa-11-aza-1(4,2),2(2,5)-dioxazola-3(3,4)-indola-4(1,2),7(1,3)-dibenzenacyclododecaphane-31-carboxylate