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(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

CAS号：381214-18-2

英文名：(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

分子式：C36H59NO6Si

分子量：629.942

合成路线

335060-56-5

((2R,4S)-5-Azido-2,4-dimethyl-pentyloxy)-tert-butyl-dimethyl-silane

381214-18-2

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

335060-50-9

(2R,4S)-5-Azido-2,4-dimethyl-pentan-1-ol

381214-18-2

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

381214-12-6

(2R,4S,5S,7S)-4-((tert-butyldimethylsilyl)oxy)-5-hydroxy-7-methyl-3-oxo-10-(triethylsilyl)dec-9-yne-1,2-diyl dibenzoate

381214-18-2

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

381214-09-1

(S)-3-Methyl-6-triethylsilanyl-hex-5-yn-1-ol

381214-18-2

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

214260-96-5

(4R,2''RS)-4-methyl-6-(2-tetrahydropyranyloxy)1-hexyne

381214-18-2

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(4-methoxy-benzyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester

上游原料

((2R,4S)-5-Azido-2,4-dimethyl-pentyloxy)-tert-butyl-dimethyl-silane (S)-3-Methyl-6-triethylsilanyl-hex-5-yn-1-ol (4R,2''RS)-4-methyl-6-(2-tetrahydropyranyloxy)1-hexyne (2R,4S,5S,7S)-4-((tert-butyldimethylsilyl)oxy)-5-hydroxy-7-methyl-3-oxo-10-(triethylsilyl)dec-9-yne-1,2-diyl dibenzoate (2R,4S)-5-Azido-2,4-dimethyl-pentan-1-ol

下游产品

(2S,3S,5R,8S,10R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(1S,3S)-1-(tert-butyl-dimethyl-silanyloxy)-3-methyl-hex-5-ynyl]-8,10-dimethyl-1-oxa-6-aza-spiro[4.5]decane-6-carboxylic acid tert-butyl ester