[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

CAS号：383125-30-2

英文名：[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

分子式：C40H54O5Si

分子量：642.939

合成路线

(R)-2-((4S,5R,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

(R)-2-((4S,5R,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(R)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

(R)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

63914-23-8

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(2R,3S,4R)-4-Benzyloxy-2-benzyloxymethyl-3-methoxymethoxy-3,4-dihydro-2H-pyran

(2R,3S,4R)-4-Benzyloxy-2-benzyloxymethyl-3-methoxymethoxy-3,4-dihydro-2H-pyran

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(2R,4R)-4-Benzyloxy-2-benzyloxymethyl-6-methoxy-dihydro-pyran-3-one

(2R,4R)-4-Benzyloxy-2-benzyloxymethyl-6-methoxy-dihydro-pyran-3-one

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(S)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

(S)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(R)-2-[(2S,4R,5S,6R)-4-Benzyloxy-6-benzyloxymethyl-5-hydroxy-5-((S)-1-hydroxy-propyl)-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

(R)-2-[(2S,4R,5S,6R)-4-Benzyloxy-6-benzyloxymethyl-5-hydroxy-5-((S)-1-hydroxy-propyl)-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(R)-2-((4S,5S,6R,8S,10R)-10-Benzyloxy-6-benzyloxymethyl-4-ethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

(R)-2-((4S,5S,6R,8S,10R)-10-Benzyloxy-6-benzyloxymethyl-4-ethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(R)-2-((4S,5R,6R,8S,10R)-4-Ethyl-10-hydroxy-6-hydroxymethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

(R)-2-((4S,5R,6R,8S,10R)-4-Ethyl-10-hydroxy-6-hydroxymethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

(R)-2-((4S,5R,6S,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-phenylselanylmethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

(R)-2-((4S,5R,6S,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-phenylselanylmethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

[(S)-2-((4S,5R,8S,10S)-10-Benzyloxy-4-ethyl-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentyloxy]-tert-butyl-diphenyl-silane

上游原料

(R)-2-((4S,5R,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-methylene-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester (R)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester (2R,3S,4R)-4-Benzyloxy-2-benzyloxymethyl-3-methoxymethoxy-3,4-dihydro-2H-pyran (R)-2-((4S,5R,6S,8S,10R)-4-Ethyl-10-hydroxy-2,2-dimethyl-6-phenylselanylmethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester (2R,4R)-4-Benzyloxy-2-benzyloxymethyl-6-methoxy-dihydro-pyran-3-one (R)-2-((4S,5R,6R,8S,10R)-4-Ethyl-10-hydroxy-6-hydroxymethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester (R)-2-((4S,5S,6R,8S,10R)-10-Benzyloxy-6-benzyloxymethyl-4-ethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]dec-8-yl)-pentanoic acid methyl ester (S)-2-[(2S,4R,6S)-4-Benzyloxy-6-benzyloxymethyl-5-prop-(E)-ylidene-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester (R)-2-[(2S,4R,5S,6R)-4-Benzyloxy-6-benzyloxymethyl-5-hydroxy-5-((S)-1-hydroxy-propyl)-tetrahydro-pyran-2-yl]-pentanoic acid methyl ester

下游产品

(2R,3S,4S,6S,8S)-8-Benzyloxy-6-[(S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-butyl]-2-ethyl-1,5-dioxa-spiro[2.5]octan-4-ol (R)-2-((2R,3R,4S,6S,8S)-2-Ethyl-4,8-dihydroxy-1,5-dioxa-spiro[2.5]oct-6-yl)-1-[2-hydroxy-3-hydroxymethyl-4-methoxymethoxy-5-((R)-1-methoxy-2-methyl-propyl)-phenyl]-pentan-1-one [(S)-2-((2R,3S,4S,6S,8S)-4,8-Bis-benzyloxy-2-ethyl-1,5-dioxa-spiro[2.5]oct-6-yl)-pentyloxy]-tert-butyl-diphenyl-silane (4S,5R,8S,10S)-10-Benzyloxy-8-[(S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-butyl]-4-ethyl-2,2-dimethyl-1,3,7-trioxa-spiro[4.5]decan-6-one (R)-2-((2R,3S,4S,6S,8S)-4,8-Bis-benzyloxy-2-ethyl-1,5-dioxa-spiro[2.5]oct-6-yl)-1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-2,4-bis-methoxymethoxy-5-((R)-1-methoxy-2-methyl-propyl)-phenyl]-pentan-1-one