百科

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

CAS号：389633-40-3

英文名：(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

分子式：C33H38O7Si

分子量：574.736

合成路线

5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-1-phenyl-D-ribofuranose

5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-1-phenyl-D-ribofuranose

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

2,3-异亚丙氧基-D-呋喃核糖苷

2,3-异亚丙氧基-D-呋喃核糖苷

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

5-Acetyl-2,3-O-isopropyliden-D-ribonolactone

5-Acetyl-2,3-O-isopropyliden-D-ribonolactone

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

131064-98-7

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

[(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde

[(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

(1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane

上游原料

5-Acetyl-2,3-O-isopropyliden-D-ribonolactone 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-1-phenyl-D-ribofuranose [(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde 2,3-异亚丙氧基-D-呋喃核糖苷

下游产品

5-bromo-1-[(1R,3S,5S,7R,8R)-8-hydroxy-7-(hydroxymethyl)-5-phenyl-2,6-dioxabicyclo[3.3.0]octan-3-yl]uracil N4-benzoyl-5-fluoro-1-[(1R,3S,5S,7R,8R)-8-hydroxy-7-(hydroxymethyl)-5-phenyl-2,6-dioxabicyclo[3.3.0]octan-3-yl]cytosine (1'S,3'R,4'R,5'R,7'R)-N4-benzoyl-1-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)cytosine (1'S,3'R,4'R,5'R,7'R)-N4-benzoyl-1-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)-5-methylcytosine (1'S,3'R,4'R,5'R,7'R)-N2-isobutyryl-9-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)guanine 5-fluoro-1-[(1R,3S,5S,7R,8R)-8-hydroxy-7-(hydroxymethyl)-5-phenyl-2,6-dioxabicyclo[3.3.0]octan-3-yl]uracil (1'S,3'R,4'R,5'R,7'R)-N6-benzoyl-9-{4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}adenine (1'S,3'R,4'R,5'R,7'S)-N4-benzoyl-1-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)cytosine N4-benzoyl-5-bromo-1-[(1R,3S,5S,7R,8R)-8-hydroxy-7-(hydroxymethyl)-5-phenyl-2,6-dioxabicyclo[3.3.0]octan-3-yl]cytosine (1S,3R,4R,5R)-4-hydroxy-3-hydroxymethyl-1-phenyl-2,6-dioxabicyclo[3.3.0]octane (1'S,3'R,4'R,5'R,7'S)-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)thymine (1S,3R,4R,5R)-4-acetoxy-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-2,6-dioxabicyclo[3.3.0]octane (1'S,3'R,4'R,5'R,7'S)-N4-benzoyl-1-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)-5-methylcytosine (1'S,3'R,4'R,5'R,7'S)-N6-benzoyl-9-{4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}adenine