百科

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

CAS号：393589-25-8

英文名：(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

分子式：C29H57NO5Si

分子量：527.852

合成路线

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid methyl ester

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid methyl ester

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

158355-82-9

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid

上游原料

(R)-2-((2R,5S)-5-{(1R,2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-[(2R,5S)-5-((R)-2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid methyl ester

下游产品

(S)-2-((2R,5S)-5-{(S)-2-[(R)-2-((2R,5S)-5-{(1S,2S,3S)-3-[(2R,5S)-5-((R)-2-Dimethylamino-pentyl)-tetrahydro-furan-2-yl]-2-hydroxy-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-pentyl}-tetrahydro-furan-2-yl)-propionic acid (S)-2-((2R,5S)-5-{(1R,2S)-2-[(R)-2-((2R,5S)-5-{(1S,2S,3S)-3-[(2R,5S)-5-((R)-2-Dimethylamino-pentyl)-tetrahydro-furan-2-yl]-2-hydroxy-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-1-methyl-pentyl}-tetrahydro-furan-2-yl)-propionic acid 2-(5-{2-[2-(5-{3-[5-(2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-2-hydroxy-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-1-methyl-pentyl}-tetrahydro-furan-2-yl)-propionic acid benzyl ester 2-(5-{2-(tert-butyl-dimethyl-silanyloxy)-3-[5-(2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid 1-{1-[5-(1-benzyloxycarbonyl-ethyl)-tetrahydro-furan-2-yl]-ethyl}-butyl ester 2-(5-{2-(tert-butyl-dimethyl-silanyloxy)-3-[5-(2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionic acid 1-[5-(1-benzyloxycarbonyl-ethyl)-tetrahydro-furan-2-ylmethyl]-butyl ester 2-(5-{2-[2-(5-{3-[5-(2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-2-hydroxy-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-1-methyl-pentyl}-tetrahydro-furan-2-yl)-propionic acid benzyl ester (R)-2-((2R,5S)-5-{(1R,2S)-2-[(R)-2-((2R,5S)-5-{(1S,2S,3S)-3-[(2R,5S)-5-((R)-2-Dimethylamino-pentyl)-tetrahydro-furan-2-yl]-2-hydroxy-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-1-methyl-pentyl}-tetrahydro-furan-2-yl)-propionic acid 2-(5-{2-[2-(5-{2-(tert-butyl-dimethyl-silanyloxy)-3-[5-(2-dimethylamino-pentyl)-tetrahydro-furan-2-yl]-1-methyl-butyl}-tetrahydro-furan-2-yl)-propionyloxy]-1-methyl-pentyl}-tetrahydro-furan-2-yl)-butyric acid benzyl ester