化合物简介
Dacarbazine (brand names DTIC, DTIC-Dome; also known as DIC or imidazole carboxamide) is an antineoplastic chemotherapy drug used in the treatment of various cancers, among them malignant melanoma, Hodgkin's lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
基本信息
中文名称
达卡巴嗪
英文名称
dacarbazine
中文别名
氮烯咪胺、5-(3,3-二甲基-1-三氮烯)咪唑-4-羧酰胺
英文别名
dtic-aome、5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide、DTIC、DTIE、dtic-dome、Dacarbazine、5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide DTIC、5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide,DTIC、5-(3,3-dimethyl-l-triazenyl)imidazole-4-carboxamide、1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-、5-(3,3-dimethyltriazen-1-yl)-imidazole-4-carboxamide、DICARBAZINE、5-(3,3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide、5-(3,3-dimethyl-1-triazenyl)imidazole-4-carboxamide、deticene
CAS号
4342-03-4
分子式
C6H10N6O
分子量
182.183
精确质量
182.092
PSA
99.73
LOGP
0.7692
编号系统
MDL号
MFCD00057167
物化性质
外观与性状
淡黄色或微红的粉末
密度
1.48 g/cm3
沸点
456.3ºC at 760 mmHg
熔点
199-205°C
闪点
229.7ºC
折射率
1.678
稳定性
Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件
2-8ºC
安全信息
RTECS号
NI3950000
安全说明
S53-S36/37/39-S45
危险类别码
R45; R46; R20/21/22; R36/37/38
WGK Germany
3
海关编码
2933290090
危险品标志
T
危险标志
GHS07, GHS08
信号词
Danger
危险性防范说明
P201; P261; P280; P305 + P351 + P338; P308 + P313
危险性描述
H302 + H312 + H332; H315; H319; H335; H340; H350
