百科

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

CAS号：445306-61-6

英文名：(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

分子式：C34H47NO6Si

分子量：593.826

合成路线

(6S)-6-(4-methoxybenzyloxy)-4-methyl-5,6-dihydro-2H-pyran-2-one

(6S)-6-(4-methoxybenzyloxy)-4-methyl-5,6-dihydro-2H-pyran-2-one

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(4S,5S)-4,5-bis-1-[(S)-allyloxy-3-methylbut-3-enyl]-2,2-dimethyl-[1,3]-dioxolane

(4S,5S)-4,5-bis-1-[(S)-allyloxy-3-methylbut-3-enyl]-2,2-dimethyl-[1,3]-dioxolane

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(S)-3,6-dihydro-4-methyl-2H-pyran-2-carbaldehyde

(S)-3,6-dihydro-4-methyl-2H-pyran-2-carbaldehyde

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(S)-2-allyloxy-4-methyl-1-trityloxy-4-pentene

(S)-2-allyloxy-4-methyl-1-trityloxy-4-pentene

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

(2E,7E,5S,6S)-5-(tert-butyldiphenylsilanyloxy)-6-(methoxymethoxy)-8-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]-octa-2,7-dienoic acid N-methoxy-N-methyl-amide

上游原料

(S)-3,6-dihydro-4-methyl-2H-pyran-2-carbaldehyde (4S,5S)-4,5-bis-1-[(S)-allyloxy-3-methylbut-3-enyl]-2,2-dimethyl-[1,3]-dioxolane (S)-2-allyloxy-4-methyl-1-trityloxy-4-pentene (6S)-6-(4-methoxybenzyloxy)-4-methyl-5,6-dihydro-2H-pyran-2-one

下游产品

C.2-C.3-(E) des-epoxy-laulimalide (Z)-4-[(2R,6R)-6-((S)-2,4-Dimethyl-pent-4-enyl)-5,6-dihydro-2H-pyran-2-yl]-but-2-enoic acid (E)-(1S,2S)-1-[(E)-3-((4R,6R)-4,6-dimethyl-[1,3]dioxan-2-yl)-allyl]-2-methoxymethoxy-4-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-but-3-enyl ester (1E,6E,3S,4S)-7-[(4R,6R)-(4,6-dimethyl-[1,3]dioxan-2-yl)]-3-methoxymethoxy-1-[(2S)-(4-methyl-3,6-dihydro-2H-pyran-2-yl)]-hepta-1,6-dien-4-ol (3Z,9E)-(1R,7S,11S,15S,17R)-7-[(E)-(S)-1-Methoxymethoxy-3-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-15-methyl-13-methylene-11-((R)-1-methyl-3-oxo-butoxy)-6,21-dioxa-bicyclo[15.3.1]henicosa-3,9,19-trien-5-one