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3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

CAS号：454186-12-0

英文名：3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

分子式：C44H47NO8

分子量：717.846

合成路线

N-[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-2-[4-(5-formyl-2-isopropoxy-phenoxy)-phenyl]-N-((S)-1-phenyl-ethyl)-acetamide

N-[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-2-[4-(5-formyl-2-isopropoxy-phenoxy)-phenyl]-N-((S)-1-phenyl-ethyl)-acetamide

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-benzyloxy-4,5-dimethoxyphenylacetonitrile

3-benzyloxy-4,5-dimethoxyphenylacetonitrile

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

5320-34-3

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenol

5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenol

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

(3-Bromo-4,5-dimethoxy-benzyloxy)-tert-butyl-dimethyl-silane

(3-Bromo-4,5-dimethoxy-benzyloxy)-tert-butyl-dimethyl-silane

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

5-tert-butyldimethylsiloxymethyl-2,3-dimethoxyphenol

5-tert-butyldimethylsiloxymethyl-2,3-dimethoxyphenol

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

1-benzyloxy-5-tert-butyldimethylsilyl-2,3-dimethoxybenzene

1-benzyloxy-5-tert-butyldimethylsilyl-2,3-dimethoxybenzene

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine

[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-N-((S)-1-phenyl-ethyl)-acetamide

2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-N-((S)-1-phenyl-ethyl)-acetamide

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

{4-[5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenoxy]-phenyl}-acetic acid

{4-[5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenoxy]-phenyl}-acetic acid

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester

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上游原料

3-benzyloxy-4,5-dimethoxyphenylacetonitrile 5-tert-butyldimethylsiloxymethyl-2,3-dimethoxyphenol 3-benzyloxy-4,5-dimethoxybenzyl alcohol {4-[5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenoxy]-phenyl}-acetic acid N-[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-2-[4-(5-formyl-2-isopropoxy-phenoxy)-phenyl]-N-((S)-1-phenyl-ethyl)-acetamide [2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine 1-benzyloxy-5-tert-butyldimethylsilyl-2,3-dimethoxybenzene (3-Bromo-4,5-dimethoxy-benzyloxy)-tert-butyl-dimethyl-silane 5-(tert-Butyl-dimethyl-silanyloxymethyl)-2-isopropoxy-phenol (3-Bromo-4-isopropoxy-benzyloxy)-tert-butyl-dimethyl-silane 2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-N-((S)-1-phenyl-ethyl)-acetamide

下游产品

(S)-8-{4-[2-(Ethoxycarbonyl-methyl-amino)-ethyl]-2-nitro-phenoxy}-1-[4-(2-isopropoxy-5-methoxycarbonyl-phenoxy)-benzyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 3-[4-((S)-8-{4-[2-(Ethoxycarbonyl-methyl-amino)-ethyl]-2-methoxy-phenoxy}-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-phenoxy]-4-isopropoxy-benzoic acid methyl ester 3-{4-[(S)-6,7-Dimethoxy-8-(6-methoxy-2-methyl-1-oxo-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-phenoxy}-4-isopropoxy-benzoic acid methyl ester