百科

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

CAS号：455262-36-9

英文名：ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

分子式：C26H27Cl2N3O4

分子量：516.416

合成路线

3,5-dichloroisonicotinoyl chloride

3,5-dichloroisonicotinoyl chloride

(S)-3-(4-amino-phenyl)-2-(3-oxo-spiro[3.5]non-1-en-1-ylamino)-propionic acid ethyl ester

(S)-3-(4-amino-phenyl)-2-(3-oxo-spiro[3.5]non-1-en-1-ylamino)-propionic acid ethyl ester

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

N-isonicotinoyl-(L)-4-aminophenylalanine

N-isonicotinoyl-(L)-4-aminophenylalanine

1-keto-3-hydroxyspiro[3,5]-non-2-ene

1-keto-3-hydroxyspiro[3,5]-non-2-ene

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

ethyl (2S)-2-[(3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

上游原料

3,5-dichloroisonicotinoyl chloride (S)-3-(4-amino-phenyl)-2-(3-oxo-spiro[3.5]non-1-en-1-ylamino)-propionic acid ethyl ester 1-keto-3-hydroxyspiro[3,5]-non-2-ene N-isonicotinoyl-(L)-4-aminophenylalanine

下游产品

ethyl (2S)-2-[(2-iodo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate ethyl (2S)-2-[(2-chloro-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoic acid