百科

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

CAS号：459871-10-4

英文名：Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

分子式：C34H48N6O9S

分子量：716.845

合成路线

459871-08-0

ethyl 4-azido-2-(hydroxymethyl)-5-methylpyrimidine-6-carboxylate

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

147911-87-3

6-amino-4-(ethoxycarbonyl)-5-methylpyrimidine-2-carboxaldehyde

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

74536-28-0

ethyl 6-chloro-2-formyl-5-methylpyrimidine-4-carboxylate

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

108492-14-4

tert-butyl 3-azido-(2S)-[(tert-butoxycarbonyl)amino]propionate

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

459871-14-8

tert-butyl(2S)-[(tert-butoxycarbonyl)amino]-3-phenylmethanesulfonyloxypropionate

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

142582-30-7

459871-10-4

Nα-(tert-butoxycarbonyl)-Nβ-[3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)-1-[(4S,5R)-4-methyl-5-phenyl-2-oxazolidinyl]-2-methylthiopropion-3-yl]-(S)-β-aminoalanine tert-butyl ester

上游原料

ethyl 4-azido-2-(hydroxymethyl)-5-methylpyrimidine-6-carboxylate tert-butyl 3-azido-(2S)-[(tert-butoxycarbonyl)amino]propionate 6-amino-4-(ethoxycarbonyl)-5-methylpyrimidine-2-carboxaldehyde ethyl 6-chloro-2-formyl-5-methylpyrimidine-4-carboxylate tert-butyl(2S)-[(tert-butoxycarbonyl)amino]-3-phenylmethanesulfonyloxypropionate

下游产品

Nα-(tert-butoxycarbonyl)-Nβ-[1-amino-3(S)-(4-amino-6-carboethoxy-5-methylpyrimidin-2-yl)propion-3-yl]-(S)-β-aminoalanine tert-butyl ester Nα-(tert-butoxycarbonyl)-Nβ-[1-amino-3(S)-(4-amino-6-carboxy-5-methylpyrimidin-2-yl)propion-3-yl]-(S)-β-aminoalanine tert-butyl ester