百科

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

CAS号：466651-87-6

英文名：(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

分子式：C19H25N3O6S2

分子量：455.548

合成路线

(2S,4R)-2-formyl-4-tert-butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine

(2S,4R)-2-formyl-4-tert-butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

(4R,2S)-4-(tert-butyldimethylsilanyloxy)-2-[((R)-4-ethoxycarbonyl)thiazolidin-2-yl]-1-(p-nitrobenzyloxycarbonyl)pyrrolidine

(4R,2S)-4-(tert-butyldimethylsilanyloxy)-2-[((R)-4-ethoxycarbonyl)thiazolidin-2-yl]-1-(p-nitrobenzyloxycarbonyl)pyrrolidine

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

(S)-2-[(2S,4S)-4-Mercapto-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-[1,3]thiazinane-4-carboxylic acid ethyl ester

上游原料

(2S,4R)-2-formyl-4-tert-butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine (4R,2S)-4-(tert-butyldimethylsilanyloxy)-2-[((R)-4-ethoxycarbonyl)thiazolidin-2-yl]-1-(p-nitrobenzyloxycarbonyl)pyrrolidine

下游产品

(4R,5S,6S)-3-[(3S,5S)-5-((S)-4-Ethoxycarbonyl-[1,3]thiazinan-2-yl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester