Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

CAS号：475291-43-1

英文名：Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

分子式：C28H43NO10S

分子量：585.707

合成路线

N-[(R)-1-benzyloxy-2-{(1R,5R,7R,8S)-3,3-dimethyl-8-methoxymethoxy-2,4,6-trioxabicyclo[3.3.0]octane-7-yl}but-3-en-2-yl]trichloroacetamide

N-[(R)-1-benzyloxy-2-{(1R,5R,7R,8S)-3,3-dimethyl-8-methoxymethoxy-2,4,6-trioxabicyclo[3.3.0]octane-7-yl}but-3-en-2-yl]trichloroacetamide

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

(Z)-4-benzyloxy-3-{(1R,5R,7R,8S)-8-methoxymethoxy-3,3-dimethyl-2,4,6-trioxabicyclo[3.3.0]oct-7-yl}but-2-en-1-ol

(Z)-4-benzyloxy-3-{(1R,5R,7R,8S)-8-methoxymethoxy-3,3-dimethyl-2,4,6-trioxabicyclo[3.3.0]oct-7-yl}but-2-en-1-ol

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

ethyl (E,4S,5R,6R,7S)-7-benzyloxymethyl-4,5:6,8-bis(isopropylidenedioxy)-7-(trichloroacetamido)oct-2-enoate

ethyl (E,4S,5R,6R,7S)-7-benzyloxymethyl-4,5:6,8-bis(isopropylidenedioxy)-7-(trichloroacetamido)oct-2-enoate

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

Methanesulfonic acid (E)-3-[(4S,5R)-5-((4R,5S)-5-benzyloxymethyl-5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-allyl ester

上游原料

(Z)-4-benzyloxy-3-{(1R,5R,7R,8S)-8-methoxymethoxy-3,3-dimethyl-2,4,6-trioxabicyclo[3.3.0]oct-7-yl}but-2-en-1-ol ethyl (E,4S,5R,6R,7S)-7-benzyloxymethyl-4,5:6,8-bis(isopropylidenedioxy)-7-(trichloroacetamido)oct-2-enoate N-[(R)-1-benzyloxy-2-{(1R,5R,7R,8S)-3,3-dimethyl-8-methoxymethoxy-2,4,6-trioxabicyclo[3.3.0]octane-7-yl}but-3-en-2-yl]trichloroacetamide

下游产品

tert-butyl N-[(E,2S,3R,4R,5S)-2-benzyloxymethyl-8-bromo-1,3:4,5-bis(isopropylidenedioxy)oct-6-en-2-yl]carbamate