百科

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

CAS号：485755-34-8

英文名：1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

分子式：C28H32N2O9S

分子量：572.627

合成路线

3-C-allyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

3-C-allyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

(R)-1-((3aR,5R,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol

(R)-1-((3aR,5R,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

1-(3-C-allyl-3-O-benzyl-4-C-tosyloxymethyl-β-D-ribofuranosyl)thymine

上游原料

(R)-1-((3aR,5R,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol 3-C-allyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

下游产品

(1R,3R,4R,7S)-1-(4,4'-dimethoxytrityl)oxymethyl-7-hydroxy-7-(2-hydroxyethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane Toluene-4-sulfonic acid (2S,3S,4R,5R)-3-benzyloxy-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(2-hydroxy-ethyl)-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityl)oxymethyl-7-hydroxy-7-(2-levulinoyloxyethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane (1R,3R,4R,7S)-7-allyl-7-benzyloxy-1-(4,4'-dimethoxytrityl)oxymethyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane (1R,3R,4R,7S)-7-benzyloxy-1-(4,4'-dimethoxytrityl)oxymethyl-7-(2-hydroxyethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane Toluene-4-sulfonic acid (2S,3S,4R,5R)-3-allyl-3-benzyloxy-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (1S,6R,8R,9R)-1-hydroxy-6-hydroxymethyl-9-methoxy-8-(thymin-1-yl)-4,7-dioxabicyclo[4.3.0]nonane