百科

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

CAS号：488808-12-4

英文名：N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

分子式：C32H61NO5Si

分子量：567.916

合成路线

(2E)-1-chloropentadecene

(2E)-1-chloropentadecene

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

(2R,3S)-1-chloropentadecane-2,3-diol

(2R,3S)-1-chloropentadecane-2,3-diol

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

(+/-)-1-trimethylsilyl-1-pentadecyn-3-ol

(+/-)-1-trimethylsilyl-1-pentadecyn-3-ol

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

(4R,5S)-4-chloromethyl-5-dodecyl-2,2-dimethyl-1,3-dioxolane

(4R,5S)-4-chloromethyl-5-dodecyl-2,2-dimethyl-1,3-dioxolane

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

N-tert-butoxycarbonyl-(4S,1'R,4'S)-4-[4'-(tert-butyldimethylsilyloxy)-1'-hydroxy-2'-hexadecynyl]-2,2-dimethyl-1,3-oxazolidine

上游原料

(2E)-1-chloropentadecene (+/-)-1-trimethylsilyl-1-pentadecyn-3-ol (2R,3S)-1-chloropentadecane-2,3-diol (4R,5S)-4-chloromethyl-5-dodecyl-2,2-dimethyl-1,3-dioxolane

下游产品

(2S,4R,5S,3'S)-5-tert-butoxycarbamido-4-(3'-hydroxypentadecyl)-2-phenyl-1,3-dioxacyclohexane tert-butyl (1S,2S,4R,6R)-6-dodecyl-2-phenylhexahydro[1,3]dioxino[5,4-b]pyridine-5-carboxylate (2S,3R,6S)-2-tert-butoxycarbamidoctadecane-1,3,6-triol (2S,3R,6S)-2-octanoylamido-4-octadecyne-1,3,6-triol tert-butyl (4S,1'R,4'S)-4-(1',4'-dihydroxyhexadecyl)-2,2-dimethyl-3-oxazolidinecarboxylate (-)-Deoxoprosophylline