百科

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

CAS号：491577-99-2

英文名：(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

分子式：C16H17IO4

分子量：400.208

合成路线

(1R,4S,5S)-1-(benzyloxymethyl)-2-en-4,5-(O-isopropylidenedioxy)-cyclopentan-1-ol

(1R,4S,5S)-1-(benzyloxymethyl)-2-en-4,5-(O-isopropylidenedioxy)-cyclopentan-1-ol

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose

5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

(3aR,6aR)-6-benzyloxymethyl-5-iodo-2,2-dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

上游原料

(1R,4S,5S)-1-(benzyloxymethyl)-2-en-4,5-(O-isopropylidenedioxy)-cyclopentan-1-ol 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose

下游产品

O-((8S,9S,9aR)-8-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-7-fluoro-2,2,4,4-tetraisopropyl-6,8,9,9a-tetrahydrocyclopenta[f][1,3,5,2,4]trioxadisilocin-9-yl) O-phenyl carbonothioate 1-[(1S,2S,3R)-5-fluoro-3,6-(tetraisopropyldisiloxane-1,3-diyl)cylopent-4(5)-en-2-ol-1-yl]uracil 1-[(1S,4S)-2-fluoro-4,6-(tetraisopropyldisiloxane-1,3-diyl)cylopent-2(3)-en-1-yl]uracil