百科

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

CAS号：496789-44-7

英文名：(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

分子式：C41H41BrN4O8

分子量：797.69

合成路线

Boc-L-Val-L-Ser-OMe

Boc-L-Val-L-Ser-OMe

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

Boc-L-Val-L-Ozn-4-COOMe

Boc-L-Val-L-Ozn-4-COOMe

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

(S)-2-(1-tert-butoxycarbonylamino-2-methyl)propyloxazole-4-methanol

(S)-2-(1-tert-butoxycarbonylamino-2-methyl)propyloxazole-4-methanol

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

(S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester

上游原料

Boc-L-Val-L-Ser-OMe (S)-2-(1-tert-butoxycarbonylamino-2-methyl)propyloxazole-4-methanol Boc-L-Val-L-Ozn-4-COOMe

下游产品

(S)-2-Benzyloxycarbonylamino-3-(3-{(S)-3-[4-benzyloxymethyl-2-((S)-1-tert-butoxycarbonylamino-2-methyl-propyl)-oxazol-5-yl]-7-bromo-1-methoxymethyl-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-methoxymethoxy-phenyl)-propionic acid benzyl ((3S,5'S,8'S)-4'-((benzyloxy)methyl)-7-bromo-6'-hydroxy-8'-isopropyl-1-(methoxymethyl)-2,6'-dioxospiro[indoline-3,2'-7-aza-1(5,2)-oxazola-3(1,3)-benzenacyclooctaphan]-5'-yl)carbamate benzyl ((3S,5'S,8'S)-4'-((benzyloxy)methyl)-7-bromo-8'-isopropyl-6'-(methoxymethoxy)-1-(methoxymethyl)-2,6'-dioxospiro[indoline-3,2'-7-aza-1(5,2)-oxazola-3(1,3)-benzenacyclooctaphan]-5'-yl)carbamate