化合物简介
Benorilate (INN), or benorylate, is an ester-linked codrug of aspirin with paracetamol. It is used as an anti-inflammatory and antipyretic medication. In the treatment of childhood fever, it has been shown to be inferior to paracetamol and aspirin taken separately. In addition, because it is converted to aspirin, benorylate is not recommended in children due to concerns about Reye syndrome.
基本信息
中文名称
贝诺酯
英文名称
4-Acetamidophenyl 2-acetoxybenzoate
中文别名
普加巴林、2-乙酰氧基苯甲酸4-乙酰氨基苯酯、4-乙酰氨基苯、阿司匹林对乙酰氨基酚酯、2-乙酰氧基苯甲酸-4-乙酰氨基苯酯
英文别名
(4-acetamidophenyl) 2-acetyloxybenzoate、Aspirin Acetaminophen Ester、4-Acetamidophenyl 2-Acetoxybenzoate
CAS号
5003-48-5
分子式
C17H15NO5
分子量
313.305
精确质量
313.095
PSA
81.7
LOGP
2.8625
编号系统
UNII
W1QX9DV96G
物化性质
密度
1.286 g/cm3
沸点
537.8ºC at 760 mmHg
熔点
177-181ºC
闪点
279ºC
折射率
1.601
安全信息
海关编码
2924299090
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