百科

[2S,8R,11S,15S]-15-(4,4-dichloropentyl)-8-hydroxymethyl-11-(1-hydroxy-1-methyl-ethyl)-2-isopropyl-14,14-dimethyl-12,16-dioxa-20-thia-3,6,9,21-tetraaza-bicyclo[16.2.1]heneicosa-1(21),18-diene-4,7,10,13,17-pentaone

CAS号：500734-33-8

英文名：[2S,8R,11S,15S]-15-(4,4-dichloropentyl)-8-hydroxymethyl-11-(1-hydroxy-1-methyl-ethyl)-2-isopropyl-14,14-dimethyl-12,16-dioxa-20-thia-3,6,9,21-tetraaza-bicyclo[16.2.1]heneicosa-1(21),18-diene-4,7,10,13,17-pentaone

分子式：C28H42Cl2N4O9S

分子量：681.625

合成路线

500734-27-0

(4S)-2-[(1S)-1-tert-butyloxycarbonylamino-2-methylpropyl]-thiazolidine-4-carboxylic acid methyl ester

500734-33-8

[2S,8R,11S,15S]-15-(4,4-dichloropentyl)-8-hydroxymethyl-11-(1-hydroxy-1-methyl-ethyl)-2-isopropyl-14,14-dimethyl-12,16-dioxa-20-thia-3,6,9,21-tetraaza-bicyclo[16.2.1]heneicosa-1(21),18-diene-4,7,10,13,17-pentaone

273202-86-1

(3S)-7,7-dichloro-3-hydroxy-2,2-dimethyl-octanoic acid methyl ester

500734-33-8

273202-87-2

(3S)-7,7-dichloro-3-hydroxy-2,2-dimethyl-octanoic acid

500734-33-8

500734-26-9

[(R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-diphenyl-silanyloxy)-propionylamino]-acetic acid allyl ester

500734-33-8

500734-25-8

(2S)-2,3-dihydroxy-3-methyl-butyric acid allyl ester

500734-33-8

上游原料

[(R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-diphenyl-silanyloxy)-propionylamino]-acetic acid allyl ester (2S)-2,3-dihydroxy-3-methyl-butyric acid allyl ester (3S)-7,7-dichloro-3-hydroxy-2,2-dimethyl-octanoic acid methyl ester (3S)-7,7-dichloro-3-hydroxy-2,2-dimethyl-octanoic acid (4S)-2-[(1S)-1-tert-butyloxycarbonylamino-2-methylpropyl]-thiazolidine-4-carboxylic acid methyl ester

下游产品

(1R,7S,14S,18S)-14-(4,4-Dichloro-pentyl)-18-(1-hydroxy-1-methyl-ethyl)-7-isopropyl-15,15-dimethyl-13,17,20-trioxa-9-thia-3,6,22,23-tetraaza-tricyclo[17.2.1.18,11]tricosa-8(23),10,19(22)-triene-2,5,12,16-tetraone