化合物简介
Sodium oxybate (USAN) (brand names Xyrem, Alcover, Anetamin, Gamanest, Gioron, Somsanit), contracted from sodium γ-hydroxybutyrate, is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of excessive daytime sleepiness (EDS) associated with narcolepsy, and by the FDA, Health Canada and in some areas of the United Kingdom National Health Service for the treatment of cataplexy associated with narcolepsy. Sodium oxybate is the sodium salt of γ-hydroxybutyric acid (GHB). Xyrem is manufactured by Jazz Pharmaceuticals in the US and Valeant Pharmaceuticals in Canada. Under the name Alcover, it is used in Italy for treatment of alcohol withdrawal and dependence.
基本信息
中文名称
4-羟基丁酸钠
英文名称
γ-Hydroxybutyric acid monosodium salt
中文别名
羟丁酸钠
英文别名
4-Hydroxybutyrate sodium、gammaoh、GHB SODIUM SALT、sodium 4-hydroxybutanoate、4-hydroxybutyric acid sodium salt、SODIUM 4-HYDROXYBUTYRATE、somsanit、SODIUM OXYBATE
CAS号
502-85-2
分子式
C4H8NaO3+
分子量
127.094
精确质量
127.037
PSA
57.53
LOGP
-0.1565
编号系统
UNII
7G33012534
物化性质
沸点
295.6ºC at 760mmHg
熔点
145-146ºC
闪点
146.8ºC
储存条件
Controlled Substance, -20ºC Freezer
安全信息
安全说明
S24/25
海关编码
2918199090