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N-Cbz-difluorooxazolidine-γ-L-glutamic acid α-tert-butyl ester γ-(2-trimethylsilyl)ethyl ester

N-Cbz-difluorooxazolidine-γ-L-glutamic acid α-tert-butyl ester γ-(2-trimethylsilyl)ethyl ester

CAS号：510713-99-2

英文名：N-Cbz-difluorooxazolidine-γ-L-glutamic acid α-tert-butyl ester γ-(2-trimethylsilyl)ethyl ester

分子式：C30H46F2N2O8Si

分子量：628.777

合成路线

H-Glu(α-OtBu)(γ-OTMSE)

H-Glu(α-OtBu)(γ-OTMSE)

(4S)-4-(2-ethoxycarbonyl-2,2-difluoroethyl)-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

(4S)-4-(2-ethoxycarbonyl-2,2-difluoroethyl)-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

N-Cbz-difluorooxazolidine-γ-L-glutamic acid α-tert-butyl ester γ-(2-trimethylsilyl)ethyl ester

N-Cbz-difluorooxazolidine-γ-L-glutamic acid α-tert-butyl ester γ-(2-trimethylsilyl)ethyl ester

上游原料

H-Glu(α-OtBu)(γ-OTMSE) (4S)-4-(2-ethoxycarbonyl-2,2-difluoroethyl)-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

下游产品

(S)-2-(2-tert-Butoxycarbonylamino-benzoylamino)-4-{(S)-1-tert-butoxycarbonyl-3-[(S)-1-tert-butoxycarbonyl-2-(4-hydroxy-3-nitro-phenyl)-ethylcarbamoyl]-propylcarbamoyl}-4,4-difluoro-butyric acid tert-butyl ester