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5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

CAS号：527704-80-9

英文名：5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

分子式：C12H16N2O8S

分子量：348.329

合成路线

(1S,3R,4R,7S)-7-benzyloxy-1-hydroxymethyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane

(1S,3R,4R,7S)-7-benzyloxy-1-hydroxymethyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

Acetic acid (3R,4S,5S)-2-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester

Acetic acid (3R,4S,5S)-2-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

3'-O-benzyl-5'-O-t-butyldiphenylsilyl-2'-O,4'-C-methylene-5-methyluridine

3'-O-benzyl-5'-O-t-butyldiphenylsilyl-2'-O,4'-C-methylene-5-methyluridine

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

5'-O-mesyl-5-methyl-2'-O,4'-C-methyleneuridine

上游原料

3'-O-benzyl-5'-O-t-butyldiphenylsilyl-2'-O,4'-C-methylene-5-methyluridine (1S,3R,4R,7S)-7-benzyloxy-1-hydroxymethyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane Acetic acid (3R,4S,5S)-2-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester

下游产品

5'-amino-5'-deoxy-5-methyl-2'-O,4'-C-methyleneuridine