百科

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

CAS号：544429-39-2

英文名：(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

分子式：C35H51NO5Si

分子量：593.869

合成路线

(E)-(2S,3R,5S)-5-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-oct-6-enoic acid methoxy-methyl-amide

(E)-(2S,3R,5S)-5-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-oct-6-enoic acid methoxy-methyl-amide

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-9-trimethylsilanyloxy-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-9-trimethylsilanyloxy-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(E)-(S)-3-Benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hex-4-enoic acid methyl ester

(E)-(S)-3-Benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hex-4-enoic acid methyl ester

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

(1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-tetradeca-1,3,5,12-tetraen-7-one

上游原料

(E)-(2S,3R,5S)-5-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-oct-6-enoic acid methoxy-methyl-amide (1E,3E,5E,12E)-(8S,9R,11S)-11-Benzyloxy-14-(tert-butyl-dimethyl-silanyloxy)-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-9-trimethylsilanyloxy-tetradeca-1,3,5,12-tetraen-7-one (E)-(S)-3-Benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hex-4-enoic acid methyl ester

下游产品

(2E,9E,11E,18E,20E,22E)-(5S,7R,8R,13S,15R,16S,17R)-7,13-Bis-benzyloxy-5-(2-benzyloxy-ethyl)-15-hydroxy-17-methoxy-8,12,16,18,22-pentamethyl-23-(2-methyl-oxazol-4-yl)-tricosa-2,9,11,18,20,22-hexaenoic acid