百科

(E)-(2S,3S,5S)-8-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-5-triisopropylsilanyloxy-oct-6-enoic acid (1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester

CAS号：544429-47-2

英文名：(E)-(2S,3S,5S)-8-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-5-triisopropylsilanyloxy-oct-6-enoic acid (1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester

分子式：C50H79NO7SSi2

分子量：894.401

合成路线

237735-58-9

methyl (4E)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-hydroxy-4-hexenoate

544429-47-2

(E)-(2S,3S,5S)-8-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-5-triisopropylsilanyloxy-oct-6-enoic acid (1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester

237735-59-0

methyl (4E,3S)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-hydroxy-4-hexenoate

544429-47-2

(E)-(2S,3S,5S)-8-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-5-triisopropylsilanyloxy-oct-6-enoic acid (1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester

237735-60-3

methyl (4E,3S)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-[(triisopropylsilyl)oxy]-4-hexenoate

544429-47-2

(E)-(2S,3S,5S)-8-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-5-triisopropylsilanyloxy-oct-6-enoic acid (1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester

上游原料

methyl (4E,3S)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-hydroxy-4-hexenoate methyl (4E,3S)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-[(triisopropylsilyl)oxy]-4-hexenoate methyl (4E)-6-[(t-butyldimethylsilyl)oxy]-4-methyl-3-hydroxy-4-hexenoate

下游产品

(1E,3E,5E,12E)-(8S,9S,11S)-14-(tert-Butyl-dimethyl-silanyloxy)-2,6,8,12-tetramethyl-1-(2-methyl-oxazol-4-yl)-11-triisopropylsilanyloxy-9-trimethylsilanyloxy-tetradeca-1,3,5,12-tetraen-7-one (Diethoxy-phosphoryl)-acetic acid (4E,6E,8E)-(1S,2S,3R)-1-[(E)-(S)-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-2-triisopropylsilanyloxy-pent-3-enyl]-3-methoxy-2,4,8-trimethyl-9-(2-methyl-oxazol-4-yl)-nona-4,6,8-trienyl ester (2E,4S,6S,7S,8R,9E,11E,13E)-3,7,9,13-tetramethyl-8-methoxy-14-(2'-methyl-4'-oxazolyl)-6-(p-nitrobenzoate)-4-[(triisopropylsilyl)oxy]-2,9,11,13-tetradecatetraen-1-al (6E,2R,3S,5S)-8-[(t-butyldimethylsilyl)oxy]-2,6-dimethyl-5-[(triisopropylsilyl)oxy]-3-[(trimethylsilyl)oxy]-6-octenal 4-nitro-benzoic acid 1-{7-[4-(3-ethoxycarbonyl-allyl)-6-methoxy-tetrahydro-pyran-2-yl]-3-methyl-2-triisopropylsilanyloxy-octa-3,5-dienyl}-3-methoxy-2,4,8-trimethyl-9-(2-methyl-oxazol-4-yl)-nona-4,6,8-trienyl ester (2E,4S,6S,7R,8RS)-1-[(t-butyldimethylsilyl)oxy]-9-(diethylphosphono)-3,7-dimethyl-4-[(triisopropylsilyl)oxy]-6-[(trimethylsilyl)oxy]-2-decaen-8-ol (6E,2R,3S,5S)-8-[(t-butyldimethylsilyl)oxy]-2,6-dimethyl-5-[(triisopropylsilyl)oxy]-3-[(trimethylsilyl)oxy]-6-octen-1-ol (2E,4S,6S,7S,8R,9E,11E,13E)-3,7,9,13-tetramethyl-8-methoxy-14-(2'-methyl-4'-oxazolyl)-6-(p-nitrobenzoate)-4-[(triisopropylsilyl)oxy]-2,9,11,13-tetradecatetraen-1-ol (2E,4S,6S,7S,8R,9E,11E,13E)-1-[(t-butyldimethylsilyl)oxy]-3,7,9,13-tetramethyl-8-methoxy-14-(2'-methyl-4'-oxazolyl)-6-(p-nitrobenzoate)-4-[(triisopropylsilyl)oxy]-2,9,11,13-tetradecatetraene 4-nitro-benzoic acid 1-{7-[6-(tert-butyl-dimethyl-silanyloxy)-4-(2-triethylsilanyloxy-ethyl)-tetrahydro-pyran-2-yl]-3-methyl-2-triisopropylsilanyloxy-octa-3,5-dienyl}-3-methoxy-2,4,8-trimethyl-9-(2-methyl-oxazol-4-yl)-nona-4,6,8-trienyl ester