百科

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

CAS号：548487-10-1

英文名：methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

分子式：C18H25N3O5S2

分子量：427.538

合成路线

methyl (1S,2R)-2-[N-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methylthiazole-4-carboxylate

methyl (1S,2R)-2-[N-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-[2-bromopropanoyl]-5-methylthiazole-4-carboxylate

methyl 2-[2-bromopropanoyl]-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl (1S,2R)-2-[N-butoxycarbonyl-2-hydroxy]-5-methylthiazole-4-carboxylate

methyl (1S,2R)-2-[N-butoxycarbonyl-2-hydroxy]-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-[(E,Z)-1-(N-Boc)amino-2-bromo-1-propenyl]-5-methylthiazole-4-carboxylate

methyl 2-[(E,Z)-1-(N-Boc)amino-2-bromo-1-propenyl]-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-3-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-3-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-(N-Boc)amino-3-bromo-2-butenoate

methyl 2-(N-Boc)amino-3-bromo-2-butenoate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

(4S,5R)-tert-butyl 4-carbamoyl-2,2,5-trimethyloxazolidine-3-carboxylate

(4S,5R)-tert-butyl 4-carbamoyl-2,2,5-trimethyloxazolidine-3-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

(4S,5R)-tert-butyl 4-carbamothioyl-2,2,5-trimethyloxazolidine-3-carboxylate

(4S,5R)-tert-butyl 4-carbamothioyl-2,2,5-trimethyloxazolidine-3-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

methyl 2-{2-[(4S,5R)-1-(butoxycarbonyl)amino-2-hydroxy]propyl-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate

上游原料

methyl 2-[2-bromopropanoyl]-5-methylthiazole-4-carboxylate (4S,5R)-tert-butyl 4-carbamothioyl-2,2,5-trimethyloxazolidine-3-carboxylate methyl 2-{2-[(4S,5R)-3-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate methyl 2-(N-Boc)amino-3-bromo-2-butenoate methyl (1S,2R)-2-[N-butoxycarbonyl-2,2,5-trimethyl(oxazolidin-4-yl)]-5-methylthiazole-4-carboxylate methyl (1S,2R)-2-[N-butoxycarbonyl-2-hydroxy]-5-methylthiazole-4-carboxylate (4S,5R)-tert-butyl 4-carbamoyl-2,2,5-trimethyloxazolidine-3-carboxylate methyl 2-[(E,Z)-1-(N-Boc)amino-2-bromo-1-propenyl]-5-methylthiazole-4-carboxylate

下游产品

methyl 2-{2-[(E,Z)-1-(butoxycarbonyl)amino-2-bromo-1-propenyl]-5-methyl(thiazol-4-yl)}-5-methylthiazole-4-carboxylate methyl 2-[2-bromopropionyl-5-methyl(thiazol-4-yl)]-5-methylthiazole-4-carboxylate