百科

(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,3S,4R,5S,6R,7S,8R)-8-(tert-butyldimethylsiloxy)-1,7-dibenzyloxy-4-hydroxy-6-(p-methoxybenzyloxy)-2-oxo-1,3,5,7-tetramethyl-decyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone

CAS号：548487-88-3

英文名：(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,3S,4R,5S,6R,7S,8R)-8-(tert-butyldimethylsiloxy)-1,7-dibenzyloxy-4-hydroxy-6-(p-methoxybenzyloxy)-2-oxo-1,3,5,7-tetramethyl-decyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone

分子式：C67H89NO13Si

分子量：1144.51

合成路线

548488-13-7

(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-hydroxy-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone

548487-88-3

(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,3S,4R,5S,6R,7S,8R)-8-(tert-butyldimethylsiloxy)-1,7-dibenzyloxy-4-hydroxy-6-(p-methoxybenzyloxy)-2-oxo-1,3,5,7-tetramethyl-decyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone

548488-11-5

(4R)-4-benzyl-3-[(2R,3S,4S,5R,6S,7R)-3-(6-benzyloxy-7-tert-butyldimethylsiloxy-3-hydroxy-5-(p-methoxyphenylmethoxy)-1-oxo-2,4,6-trimethylnonyl)]-2-oxazolidinone

548487-88-3

548488-12-6

(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-(tert-butyldimethylsiloxy)-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone

548487-88-3

上游原料

(4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-hydroxy-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone (4R)-4-benzyl-3-[(2R)-2-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-(tert-butyldimethylsiloxy)-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propionyl]-2-oxazolidinone (4R)-4-benzyl-3-[(2R,3S,4S,5R,6S,7R)-3-(6-benzyloxy-7-tert-butyldimethylsiloxy-3-hydroxy-5-(p-methoxyphenylmethoxy)-1-oxo-2,4,6-trimethylnonyl)]-2-oxazolidinone

下游产品

(2R,4S,5S,6R)-6-[(1S,3R)-3-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-(tert-butyldimethylsiloxy)-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-1-benzyloxy-1-methylbutyl]-4-[(1R)-1-carboxyeth-1-yl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxane 4-benzyl-3-{2-[6-{1-benzyloxy-3-[6-[1-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-butyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-1-methyl-butyl}-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one (2R,4S,5S,6R)-6-[(1S,3R)-3-[(2R,4S,5S,6R)-6-[(1S,2R)-1-benzyloxy-2-hydroxy-1-methylbutyl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-1-benzyloxy-1-methylbutyl]-4-[(1R)-1-carboxyeth-1-yl]-2-(p-methoxyphenyl)-5-methyl-1,3-dioxane 4-benzyl-3-{2-[6-{1-benzyloxy-3-[6-[1-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-butyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-2-hydroxy-1-methyl-butyl}-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one (9S)-dihydroerythronolide A