百科

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

CAS号：552890-55-8

英文名：1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

分子式：C35H46O8

分子量：594.735

合成路线

2,2-Dimethyl-propionic acid (2R,3S,5R,6R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester

2,2-Dimethyl-propionic acid (2R,3S,5R,6R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

2,2-Dimethyl-propionic acid (2R,3S,5R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester

2,2-Dimethyl-propionic acid (2R,3S,5R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

2,2-Dimethyl-propionic acid (2R,3S,5R,6S)-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-6-hydroxy-tetrahydro-pyran-3-yl ester

2,2-Dimethyl-propionic acid (2R,3S,5R,6S)-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-6-hydroxy-tetrahydro-pyran-3-yl ester

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10S,11S,11aS)-4',7-bis(benzyloxy)-11-hydroxy-3,4,10-trimethyldodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one

上游原料

2,2-Dimethyl-propionic acid (2R,3S,5R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester 2,2-Dimethyl-propionic acid (2R,3S,5R,6S)-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-6-hydroxy-tetrahydro-pyran-3-yl ester 2,2-Dimethyl-propionic acid (2R,3S,5R,6R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester

下游产品

1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10R,11S,11aR)-4',7-bis((tert-butyldimethylsilyl)oxy)-3,4,10-trimethyl-11-((triisopropylsilyl)oxy)dodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one 1-((2R,3S,4S,4aR,4'S,5aS,7R,8S,9aR,10R,11S,11aR)-4',7-dihydroxy-3,4,10-trimethyl-11-((triisopropylsilyl)oxy)dodecahydro-3H,3'H-spiro[dipyrano[3,2-b:2',3'-f]oxepine-2,2'-furan]-8-yl)propan-2-one