百科

11-脱氧-18beta-甘草亭酸

11-脱氧-18beta-甘草亭酸

CAS号：564-16-9

英文名：(2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-2-carboxylic acid

分子式：C30H48O3

分子量：456.7

合成路线

(2R,4aS,6aS,6bR,8aR,12aR,12bR,14bR)-10-acetoxy-2,4a,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

(2R,4aS,6aS,6bR,8aR,12aR,12bR,14bR)-10-acetoxy-2,4a,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

11-脱氧-18beta-甘草亭酸

11-脱氧-18beta-甘草亭酸

acetic acid 11-hydroxymethyl-4,4a,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydropicen-3-yl ester

acetic acid 11-hydroxymethyl-4,4a,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydropicen-3-yl ester

11-脱氧-18beta-甘草亭酸

11-脱氧-18beta-甘草亭酸

(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-Butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-ol

(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-Butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-ol

11-脱氧-18beta-甘草亭酸

11-脱氧-18beta-甘草亭酸

Acetic acid (3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yl ester

Acetic acid (3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yl ester

11-脱氧-18beta-甘草亭酸

11-脱氧-18beta-甘草亭酸

上游原料

Acetic acid (3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yl ester acetic acid 11-hydroxymethyl-4,4a,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydropicen-3-yl ester (3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bR)-11-(tert-Butyl-dimethyl-silanyloxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-ol

下游产品

methyl 2-cyano-3,11-dioxo-18βH-olean-1(2),12(13)-dien-30-oate soloxolone methyl 3-isopropylidene-A-neo-5αH-18βH-olean-12-en-30-oic acid methyl ester diphenylmethyl 11-deoxo-18β-glycyrrhetinate ethyl 3β,11α-dihydroxy-olean-12-en-30-oate methyl 3,12-dioxo-18βH-olean-30-oate methyl 12-oxoisoxazolo[2,3-d]-18β-olean-30-oate 3-isopropyl-5a,5b,7a,10,13b-pentamethyl-2,4,5,5a,5b,6,7,7a,8,9,10,11,11a,13,13a,13b-hexadecahydro-1H-cyclopenta[a]chrysene-10-carboxylic acid methyl ester ethyl 3β,11β-dihydroxy-olean-12-en-30-oate 30-nor-20β-methylamino-18β-olean-12-en-3β-ol