百科

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

CAS号：583844-11-5

英文名：1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

分子式：C36H40N2O8

分子量：628.711

合成路线

2'-O-acetyl-3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine

2'-O-acetyl-3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

3-C-allyl-3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

3-C-allyl-3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1,2-di-O-acetyl-3-C-acetoxyethyl-3,5-di-O-benzyl-4-C-(p-toluenesulfonyloxymethyl)-D-ribofuranose

1,2-di-O-acetyl-3-C-acetoxyethyl-3,5-di-O-benzyl-4-C-(p-toluenesulfonyloxymethyl)-D-ribofuranose

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

(3aR,5R,6R,6aR)-6-Benzyloxy-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-vinyl-tetrahydro-furo[2,3-d][1,3]dioxole

(3aR,5R,6R,6aR)-6-Benzyloxy-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-vinyl-tetrahydro-furo[2,3-d][1,3]dioxole

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

(3aR,5S,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde

(3aR,5S,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine

3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,3S,3aS,7aR)-3a-Benzyloxy-7a-benzyloxymethyl-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl)-3-benzyloxymethyl-5-methyl-1H-pyrimidine-2,4-dione

上游原料

(3aR,5R,6R,6aR)-6-Benzyloxy-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-vinyl-tetrahydro-furo[2,3-d][1,3]dioxole 1,2-di-O-acetyl-3-C-acetoxyethyl-3,5-di-O-benzyl-4-C-(p-toluenesulfonyloxymethyl)-D-ribofuranose (3aR,5S,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 2'-O-acetyl-3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine 3'-C-acetyloxyethyl-3',5'-di-O-benzyl-5-methyl-4'-C-(p-toluenesulfonyloxymethyl)uridine 3-C-allyl-3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

下游产品

1-{(2R,3S,3aS,7aR)-7a-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3a-hydroxy-3-methoxy-hexahydro-furo[2,3-c]pyran-2-yl}-5-methyl-1H-pyrimidine-2,4-dione