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甲氨蝶呤
CAS号:59-05-2
英文名:Methotrexate
分子式:C20H22N8O5
分子量:454.439
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合成路线
56-86-0
谷氨酸
56892-87-6
4-{[N-[(2,4-diamino-6-pteridinyl)methyl]-N-methyl]amino}benzoyl azide
59-05-2
甲氨蝶呤
7532-09-4
4-amino-4-deoxy-N10-methylpteroyl-L-glutamic acid sodium salt
59-05-2
甲氨蝶呤
138965-46-5
3-[3-((allyloxy)carbonyl)-5-oxo-1,3-oxazolan-4-yl]propanoic acid
59-05-2
甲氨蝶呤
91871-28-2
N-allyloxycarbonyl α-allyl-L-glutamate
59-05-2
甲氨蝶呤
16874-06-9
L-谷氨酸二-叔-丁基酯二苯磺酰亚胺盐
59-05-2
甲氨蝶呤
125507-17-7
2-L-alanylmethotrexate
59-05-2
甲氨蝶呤
708-74-7
6-甲基-2,4-蝶啶二胺
59-05-2
甲氨蝶呤
125507-11-1
(S)-2-(4-{[4-Amino-2-((S)-2-tert-butoxycarbonylamino-propionylamino)-pteridin-6-ylmethyl]-methyl-amino}-benzoylamino)-pentanedioic acid di-tert-butyl ester
59-05-2
甲氨蝶呤
125507-10-0
di-t-butyl ester of 2-(t-BOC-L-leucyl)methotrexate
59-05-2
甲氨蝶呤
125507-15-5
di-tert-butyl (4-(((2,4-bis((S)-2-((tert-butoxycarbonyl)amino)propanamido)pteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate
59-05-2
甲氨蝶呤
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上游原料
6-溴乙基-喋啶-2,4-二胺
3-[3-((allyloxy)carbonyl)-5-oxo-1,3-oxazolan-4-yl]propanoic acid
N-allyloxycarbonyl α-allyl-L-glutamate
水
谷氨酸
4-{[N-[(2,4-diamino-6-pteridinyl)methyl]-N-methyl]amino}benzoyl azide
2-L-alanylmethotrexate
N-[4-(甲基氨基)苯甲酰基]-L-谷氨酸
L-谷氨酸二-叔-丁基酯二苯磺酰亚胺盐
(S)-5-((4-(2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)-2-oxoethoxy)-5-methoxy-2-nitrobenzyl)oxy)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid
2-L-leucylmethotrexate
di-tert-butyl (4-(((2,4-bis((S)-2-((tert-butoxycarbonyl)amino)propanamido)pteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate
ditert-butyl 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
4-amino-4-deoxy-N10-methylpteroyl-L-glutamic acid sodium salt
4-[N-(2,4-二氨基-6-蝶啶甲基)-N-甲氨基]苯甲酸半盐酸盐n水
2,3-二溴丙醛
(S)-2-(4-{[4-Amino-2-((S)-2-tert-butoxycarbonylamino-propionylamino)-pteridin-6-ylmethyl]-methyl-amino}-benzoylamino)-pentanedioic acid di-tert-butyl ester
对甲胺基苯甲酰谷氨酸二乙酯
di-t-butyl ester of 2-(t-BOC-L-leucyl)methotrexate
6-甲基-2,4-蝶啶二胺
下游产品
bis[(6-chloro-1,3-benzodioxol-5-yl)methyl] 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
2,4-二氨基-6-羟甲基蝶啶
4-[N-(2,4-二氨基-6-蝶啶甲基)-N-甲氨基]苯甲酸半盐酸盐n水
2-[[4-[(2-氨基-4-氧代-1H-蝶啶-6-基)甲基-甲基氨基]苯甲酰基]氨基]戊烷二酸
(2S)-2-[[3-bromo-4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
N-[4-(甲基氨基)苯甲酰基]-L-谷氨酸
甲氨蝶呤二钠盐
Bromochloromethotrexate