百科

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

CAS号：627101-48-8

英文名：(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

分子式：C31H49IO6Si

分子量：672.707

合成路线

(R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide

(R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

methyl 3-(3,4-dimethoxy-benzyloxy)-2-(R)-methyl-propionate

methyl 3-(3,4-dimethoxy-benzyloxy)-2-(R)-methyl-propionate

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

methyl-(2E,5S,6E,8E)-5-(tert-butyldimethylsilyloxy)-9-iodo-3-methyl-2,6,8-nontrienoate

methyl-(2E,5S,6E,8E)-5-(tert-butyldimethylsilyloxy)-9-iodo-3-methyl-2,6,8-nontrienoate

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

(6E,10E,12E)(2R,4R,5R,13R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-5-hydroxy-13-iodo-2,4,7-trimethyl-trideca-6,10,12-trien-3-one

上游原料

methyl 3-(3,4-dimethoxy-benzyloxy)-2-(R)-methyl-propionate (R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide methyl-(2E,5S,6E,8E)-5-(tert-butyldimethylsilyloxy)-9-iodo-3-methyl-2,6,8-nontrienoate

下游产品

2-{6-[6-(tert-butyl-dimethyl-silanyloxy)-10-iodo-2-methoxy-1,4-dimethyl-deca-3,7,9-trienyl]-4-hydroxy-2-methoxy-5-methyl-tetrahydropyran-2-yl}-acetic acid methyl ester 2-{6-[6-(tert-butyl-dimethyl-silanyloxy)-10-iodo-2-methoxy-1,4-dimethyl-deca-3,7,9-trienyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-5-methyl-tetrahydropyran-2-yl}-acetic acid methyl ester (6E,10E,12E)(2R,3S,4R,5R,9R)-9-(tert-butyldimethyl-silanyloxy)-13-iodo-5-methoxy-2,4,7-trimethyl-3-triethylsilanyloxy-trideca-6,10,12-trienol (6E,10E,12E)(2R,3S,4R,5R,9R)-9-(tert-butyldimethyl-silanyloxy)-1-(3,4-dimethoxy-benzyloxy)-13-iodo-5-methoxy-2,4,7-trimethyl-3-triethylsilanyloxy-trideca-6,10,12-triene