百科

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

CAS号：647852-33-3

英文名：S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

分子式：C20H20N2O6S

分子量：416.448

合成路线

but-1-yn-4-yl thiobenzoate

but-1-yn-4-yl thiobenzoate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

5-(4-benzoylthiobut-1-ynyl)-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyuridine

5-(4-benzoylthiobut-1-ynyl)-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyuridine

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

硫代苯甲酸

硫代苯甲酸

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

3',5'-bis-O-(tert-butyldimethylsilyl)-C5-(4-hydroxy-1-butynyl)-2'-deoxyuridine

3',5'-bis-O-(tert-butyldimethylsilyl)-C5-(4-hydroxy-1-butynyl)-2'-deoxyuridine

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

S-[4-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]but-3-ynyl] benzenecarbothioate

上游原料

3',5'-bis-O-(tert-butyldimethylsilyl)-C5-(4-hydroxy-1-butynyl)-2'-deoxyuridine 硫代苯甲酸 2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine 碘苷 but-1-yn-4-yl thiobenzoate 5-(4-benzoylthiobut-1-ynyl)-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyuridine

下游产品

[(2R,3S,5R)-5-[5-[4-(tert-butyldisulfanyl)but-1-ynyl]-2,4-dioxopyrimidin-1-yl]-2-(hydroxymethyl)oxolan-3-yl] acetate