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(1R)-1,4-脱水-2-脱氧-1-(1,3-二甲基-2,4-二氧代-1,2,3,4-四氢-5-嘧啶基)-D-赤式-戊糖醇

CAS号：65358-16-9

英文名：5-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dimethylpyrimidine-2,4-dione

分子式

C11H16N2O5

熔点

密度

分子量

256.255

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(1R)-1,4-脱水-2-脱氧-1-(1,3-二甲基-2,4-二氧代-1,2,3,4-四氢-5-嘧啶基)-D-赤式-戊糖醇

英文名称

5-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dimethylpyrimidine-2,4-dione

中文别名

英文别名

1,3-dimethyl-2\'-deoxy-pseudouridine、2\'-deoxy-1,3-dimethylpseudouridine

CAS号

65358-16-9

分子式

C11H16N2O5

分子量

256.255

精确质量

256.106

PSA

93.69

LOGP

-1.7328

合成路线

103003-52-7

5-((2R,5R)-5-(hydroxymethyl)-4-oxotetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

65358-16-9

(1R)-1,4-脱水-2-脱氧-1-(1,3-二甲基-2,4-二氧代-1,2,3,4-四氢-5-嘧啶基)-D-赤式-戊糖醇

103003-60-7

5-(2'-deoxy-β-D-threo-pentofuranosyl)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione

上游原料

(+)-triisopropyl(((2R,3S)-3-((triisopropylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)silane

96760-93-9

(2R,3S)-2-Triisopropylsilanyloxymethyl-2,3-dihydro-furan-3-ol

103781-81-3

5-((2S,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

上游原料

3'-Deoxy-ψ-uridine N,N-二甲基甲酰胺二甲基缩醛脱氧假尿苷 (+)-triisopropyl(((2R,3S)-3-((triisopropylsilyl)oxy)-2,3-dihydrofuran-2-yl)methoxy)silane (2R,3S)-2-Triisopropylsilanyloxymethyl-2,3-dihydro-furan-3-ol 5-((2S,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 2'-O-Mesyl-1,3-dimethyl-ψ-uridine 2'-Chloro-2'-deoxy-3',5'-O-(1,1,3,3-tetraisopropyldisiloxanyl)-1,3-dimethyl-ψ-uridine 2'-deoxy-1,3-dimethyl-3',5'-O-(tetraisopropyldisiloxanyl)pseudouridine (2R,3R,4S,5S)-4-chloro-5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl acetate (2R,3S)-2-羟甲基-2,3-二氢呋喃-3-醇 1,3-dimethyl-5-(5'-O-(tris(1-methylethyl)silyl)-β-D-glyseropentofuran-3'-ulos-1'-yl)-2,4(1H,3H)-pyrimidinedione O-[8-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-9-yl] imidazole-1-carbothioate 1,3-dimethyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-ψ-uridine ((2R,3S)-3-((2-methoxyethoxy)methoxy)-2,3-dihydrofuran-2-yl)methanol 2'-chloro-2'-deoxy-1,3-dimethyl-ψ-uridine 2'-O-Mesyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxanyl)-1,3-dimethyl-ψ-uridine 假尿苷 2',3'-O-(1,1,3,3-Tetraisopropyldisiloxanyl)-1,3-dimethyl-ψ-uridine (1,3-dimethyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)mercuric acetate ((5aR,6R,8S,8aS)-8-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2,2,4,4-tetraisopropyltetrahydrofuro[3,4-f][1,3,5,2,4]trioxadisilepin-6-yl)methyl acetate ((5aR,6R,8S,8aS)-8-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2,2,4,4-tetraisopropyltetrahydrofuro[3,4-f][1,3,5,2,4]trioxadisilepin-6-yl)methyl trifluoromethanesulfonate 1,3-dimethyl-5-<2'-deoxy-5'-O-(tris(1-methylethyl)silyl)-β-D-erythro-pentofuranosyl>-2,4(1H,3H)-pyrimidinedione 5-[(2R,5R)-5-Hydroxymethyl-4-(2-methoxy-ethoxymethoxy)-2,5-dihydro-furan-2-yl]-1,3-dimethyl-1H-pyrimidine-2,4-dione 5-((2R,5R)-5-(hydroxymethyl)-4-oxotetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (2'R)-cis-5-<2',5'-dihydro-4'-((tris(1-methylethyl)silyl)oxy)-5'-(((tris(1-methylethyl)silyl)oxy)methyl)-2'-furanyl>-1,3-dimethyl-2,4(1H,3H)pyrimidinedione