化合物简介
1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine is an intermediate in the synthesis of Delamanid, a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
基本信息
中文名称
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine
英文名称
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine
中文别名
英文别名
CAS号
681482-80-4
分子式
C23H26F3NO4
分子量
437.452
精确质量
437.181
PSA
40.16
LOGP
5.6034