化合物简介
(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate is an intermediate in the synthesis of Delamanid, a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
基本信息
中文名称
(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl methanesulfonate
英文名称
(R)-3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl methanesulfonate
中文别名
英文别名
CAS号
681490-92-6
分子式
C8H12ClN3O6S
分子量
313.715
精确质量
313.014
PSA
135.62
LOGP
1.7759