化合物简介
A metabolite of Tamoxifen, that can be biotransformed to a quinone methide, which has the potential to alkylate DNA and may contribute to the genotoxic effects of tamoxifen. This compound slightly increases intracellular free calcium [Ca2+]i in human platelets and partially inhibits thrombin-induced [Ca2+]i elevation.
基本信息
中文名称
(Z)-1,2-二苯基-1-(4-羟基苯基)-1-丁烯
英文名称
1-phenyl-1-(p-hydroxyphenyl)-2-phenylbut-1-ene
中文别名
英文别名
(Z)-1,2-diphenyl-1-(p-hydroxyphenyl)-1-butene、(Z)-1-(4-hydroxyphenyl)-1,2-diphenyl butylene、Z-1,2-diphenyl-1-(4-hydroxyphenyl)-1-butene、(Z)-1,2-diphenyl-1-(4-hydroxyphenyl)but-1-ene、4-((E,Z)-1,2-diphenyl-but-1-enyl)-phenol、(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene、(Z)-4-(1,2-diphenyl-1-butenyl)phenol
CAS号
69967-80-2
分子式
C22H20O
分子量
300.394
精确质量
300.151
PSA
20.23
LOGP
5.7613
