百科

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

CAS号：726192-29-6

英文名：(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

分子式：C20H35NO5Si

分子量：397.581

合成路线

(+)-(1R,2S,3R,4S,5R,6S)-7-tert-butoxycarbonyl-2,3-exo-isopropylidenedioxy-6-endo-p-toluenesulfonyl-7-azabicyclo[2.2.1]heptane-5-endo-ol

(+)-(1R,2S,3R,4S,5R,6S)-7-tert-butoxycarbonyl-2,3-exo-isopropylidenedioxy-6-endo-p-toluenesulfonyl-7-azabicyclo[2.2.1]heptane-5-endo-ol

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

(1R,2R,3S,4S,4'R,5'R)-4',5'-diphenylspiro[2,3-exo-isopropylidenedioxy-7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2,2'-imidazoline]

(1R,2R,3S,4S,4'R,5'R)-4',5'-diphenylspiro[2,3-exo-isopropylidenedioxy-7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2,2'-imidazoline]

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

(+)-7-tert-butoxycarbonyl-2-[[(tert-butyl)dimethylsilyl]oxy]-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

上游原料

(1R,2R,3S,4S,4'R,5'R)-4',5'-diphenylspiro[2,3-exo-isopropylidenedioxy-7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2,2'-imidazoline] (+)-(1R,2S,3R,4S,5R,6S)-7-tert-butoxycarbonyl-2,3-exo-isopropylidenedioxy-6-endo-p-toluenesulfonyl-7-azabicyclo[2.2.1]heptane-5-endo-ol

下游产品

(3aR,4S,6S,6aS)-4-(Benzyloxycarbonylmethyl-carbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester {[(3aR,4S,6S,6aS)-5-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-4-carbonyl]-amino}-acetic acid benzyl ester