百科

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

CAS号：726192-33-2

英文名：(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

分子式：C26H38N2O8

分子量：506.589

合成路线

727417-92-7

(1S,2S,3R,4R,4'R,5'R)-4',5'-diphenylspiro[2,3-exo-isopropylidenedioxy-7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2,2'-imidazoline]

726192-33-2

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

573716-70-8

(-)-(1S,2R,3S,4R,5S,6R)-7-tert-butoxycarbonyl-2,3-exo-isopropylidenedioxy-6-endo-p-toluenesulfonyl-7-azabicyclo[2.2.1]heptane-5-endo-ol

726192-33-2

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

726192-16-1

(3aS,4R,7R,7aR)-tert-butyl 2,2-dimethyl-5-oxohexahydro-4,7-epiminobenzo[d][1,3]dioxole-8-carboxylate

726192-33-2

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

726192-18-3

7-tert-butoxycarbonyl-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]heptan-2-endo-ol

726192-33-2

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

726192-21-8

(-)-7-tert-butoxycarbonyl-2-{[(tert-butyl)dimethylsilyl]oxy}-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene

726192-33-2

(3aS,4R,6R,6aR)-4-((S)-1-Benzyloxycarbonyl-2-methyl-propylcarbamoyl)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester

上游原料

7-tert-butoxycarbonyl-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]heptan-2-endo-ol (-)-7-tert-butoxycarbonyl-2-{[(tert-butyl)dimethylsilyl]oxy}-5,6-exo-isopropylidenedioxy-7-azabicyclo[2.2.1]hept-2-ene (-)-(1S,2R,3S,4R,5S,6R)-7-tert-butoxycarbonyl-2,3-exo-isopropylidenedioxy-6-endo-p-toluenesulfonyl-7-azabicyclo[2.2.1]heptane-5-endo-ol (3aS,4R,7R,7aR)-tert-butyl 2,2-dimethyl-5-oxohexahydro-4,7-epiminobenzo[d][1,3]dioxole-8-carboxylate (1S,2S,3R,4R,4'R,5'R)-4',5'-diphenylspiro[2,3-exo-isopropylidenedioxy-7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2,2'-imidazoline]

下游产品

(S)-2-[((2R,3S,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-pyrrolidine-2-carbonyl)-amino]-3-methyl-butyric acid benzyl ester