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(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

CAS号：756834-50-1

英文名：(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

分子式：C20H21NO5

分子量：355.384

合成路线

tert-butyl (5R)-5-[(1R)-1-methylprop-2-en-1-yl]-2,2-dimethyloxazolidine-3-carboxylate

tert-butyl (5R)-5-[(1R)-1-methylprop-2-en-1-yl]-2,2-dimethyloxazolidine-3-carboxylate

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2R,3R)-4-azido-3-(tert-butyldimethylsilyloxy)-2-methylbutan-1-ol

(2R,3R)-4-azido-3-(tert-butyldimethylsilyloxy)-2-methylbutan-1-ol

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2R,3R)-4-(4-Methoxy-benzyloxy)-2-methyl-butane-1,3-diol

(2R,3R)-4-(4-Methoxy-benzyloxy)-2-methyl-butane-1,3-diol

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

(2S,3R)-4-{[(9H-fluoren-9-ylmethoxy) carbonyl]-amino}-3-hydroxy-2-methyl butanoic acid

上游原料

(2R,3R)-4-azido-3-(tert-butyldimethylsilyloxy)-2-methylbutan-1-ol tert-butyl (5R)-5-[(1R)-1-methylprop-2-en-1-yl]-2,2-dimethyloxazolidine-3-carboxylate (2R,3R)-4-(4-Methoxy-benzyloxy)-2-methyl-butane-1,3-diol

下游产品

((2R,3S)-2-Hydroxy-3-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propylcarbamoyl}-butyl)-carbamic acid 9H-fluoren-9-ylmethyl ester (9H-fluoren-9-yl)methyl ((2R,3S)-2-hydroxy-3-methyl-4-((3-((2R,3S,6S,8S)-3-methyl-8-((S)-3-methylpent-4-en-1-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)propyl)amino)-4-oxobutyl)carbamate