百科

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

CAS号：756834-71-6

英文名：2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

分子式：C30H43NO5

分子量：497.666

合成路线

2-{3-[(2R,3S,6S,8S)-8-[(S,E)-3,5-dimethyl-6-oxohept-4-en-1-yl]-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]propyl}isoindoline-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-[(S,E)-3,5-dimethyl-6-oxohept-4-en-1-yl]-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]propyl}isoindoline-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

(2S)-2-methyl-4-{(2S,6R,8R,9S)-8-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-9-methyl-1,7-dioxaspiro[5.5]undecane}butanal

(2S)-2-methyl-4-{(2S,6R,8R,9S)-8-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-9-methyl-1,7-dioxaspiro[5.5]undecane}butanal

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

(2R,3S,6R,8S)-8-[(3S)-4-hydroxy-3-methylbutyl]-2-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-3-methyl-1,7-dioxaspiro[5.5]undecane

(2R,3S,6R,8S)-8-[(3S)-4-hydroxy-3-methylbutyl]-2-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-3-methyl-1,7-dioxaspiro[5.5]undecane

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

2-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-Hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propyl}-isoindole-1,3-dione

上游原料

2-{3-[(2R,3S,6S,8S)-8-[(S,E)-3,5-dimethyl-6-oxohept-4-en-1-yl]-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]propyl}isoindoline-1,3-dione (2R,3S,6R,8S)-8-[(3S)-4-hydroxy-3-methylbutyl]-2-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-3-methyl-1,7-dioxaspiro[5.5]undecane (2S)-2-methyl-4-{(2S,6R,8R,9S)-8-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-9-methyl-1,7-dioxaspiro[5.5]undecane}butanal

下游产品

((2R,3S)-2-Hydroxy-3-{3-[(2R,3S,6S,8S)-8-((E)-(3S,6R)-6-hydroxy-3,5-dimethyl-hept-4-enyl)-3-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-propylcarbamoyl}-butyl)-carbamic acid 9H-fluoren-9-ylmethyl ester (E)-(2R,5S)-7-[(2S,6S,8R,9S)-8-(3-Amino-propyl)-9-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-3,5-dimethyl-hept-3-en-2-ol