百科

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

CAS号：75685-17-5

英文名：(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

分子式：C32H44O6Si

分子量：552.774

合成路线

5,6-Anhydro-3-deoxy-1,2-O-(1-methylethylidene)-α-D-xylo-hexofuranose

5,6-Anhydro-3-deoxy-1,2-O-(1-methylethylidene)-α-D-xylo-hexofuranose

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

1,2-O-isopropylidene-5,6-O-methoxymethylidene-3-deoxy-α-D-xylohexofuranose

1,2-O-isopropylidene-5,6-O-methoxymethylidene-3-deoxy-α-D-xylohexofuranose

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(R)-8-((3aR,5S,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid

(R)-8-((3aR,5S,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(R)-8-((3aR,5R,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid methyl ester

(R)-8-((3aR,5R,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

上游原料

(R)-8-((3aR,5R,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid methyl ester 5,6-Anhydro-3-deoxy-1,2-O-(1-methylethylidene)-α-D-xylo-hexofuranose 1,2-O-isopropylidene-5,6-O-methoxymethylidene-3-deoxy-α-D-xylohexofuranose (R)-8-((3aR,5S,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-5-ynoic acid

下游产品

methyl 8R-mesyloxy-9S,11R-dihydroxy-9,11-O-isopropylidene-eicosa-5Z,12E,14Z-trienoate methyl 8R,9S,11R-dihydroxy-9,11-O-isopropylidene-eicosa-5Z,12E,14Z-trienoate methyl 8R-tert-butyldiphenylsilyloxy-9R,11R-dihydroxy-9,11-O-isopropylidene-14-oxo-tetradeca-5Z,12E-dienoate methyl 8R-tert-butyldimethylsilyloxy-9R,11R-dihydroxy-9,11-O-isopropylidene-eicosa-5Z,12E,14-trienoate methyl 8R,9R,11R-trihydroxyeicosa-5Z,12E,14E-trienoate methyl 8R-tert-butyldiphenylsilyloxy-9R,11R-dihydroxy-9,11-O-isopropylidene-12,12-di(ethylthio)dodeca-5Z-enoate methyl 8R-acetoxy-9R,11R-dihydroxy-9,11-O-isopropylidene-eicosa-5Z,12E,14-trienoate methyl 8S,9R,11R-triacetoxy-5Z,12E,14E-eicosatrienoate