百科

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

CAS号：75796-60-0

英文名：(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

分子式：C27H43FO2

分子量：418.628

合成路线

70141-05-8

3β-tetrahydropyranyloxychol-5-en-24-yl cyanide

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72341-38-9

methyl 3β-tetrahydropyranyloxy-24-tosyloxychol-5-ene-24-carboxylate

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72341-39-0

(R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-fluoro-hexanoic acid methyl ester

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72341-36-7

(R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-iodo-hexanoic acid methyl ester

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72341-40-3

methyl 24-fluoro-3β-hydroxychol-5-ene-24-carboxylate

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

75796-59-7

3β-acetoxy-24-fluorocholest-5,7-dien-25-ol

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72349-23-6

3β-acetoxy-24-fluorocholest-5-en-25-ol

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

72341-35-6

(R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-hexanoic acid

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

82008-68-2

75796-60-0

(3S,9S,10R,13R,14R,17R)-17-((R)-4-Fluoro-5-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

上游原料

3β-acetoxy-24-fluorocholest-5-en-25-ol (R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-iodo-hexanoic acid methyl ester (R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-fluoro-hexanoic acid methyl ester (R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-hexanoic acid 3β-acetoxy-24-fluorocholest-5,7-dien-25-ol methyl 3β-tetrahydropyranyloxy-24-tosyloxychol-5-ene-24-carboxylate methyl 24-fluoro-3β-hydroxychol-5-ene-24-carboxylate 3β-tetrahydropyranyloxychol-5-en-24-yl cyanide

下游产品

24-fluoro-25-hydroxyvitamin D3