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2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

CAS号：764722-66-9

英文名：2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

分子式：C12H19F3N4O2

分子量：308.3

合成路线

N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester

Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide

上游原料

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

下游产品

5-(4-Methoxy-2-methyl-phenyl)-thiophene-2-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 4'-Ethyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 5-(4-Ethyl-phenyl)-thiophene-2-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 5-Bromo-thiophene-2-carboxylic acid {(S)-1-[(R)-3-(4,4-dimethyl-cyclohexylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-methyl-amide 5-Bromo-thiophene-2-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 4'-Trifluoromethyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide 4'-Methoxy-2'-methyl-biphenyl-4-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide