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5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

CAS号：764722-67-0

英文名：5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

分子式：C24H24F6N4O3S

分子量：562.528

合成路线

N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester

Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide

上游原料

(S)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester N-((R)-1-Benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide

下游产品

5-(4-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid [(S)-1-((R)-3-amino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-methyl-amide