百科

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

CAS号：765311-73-7

英文名：Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

分子式：C14H11FO4

分子量：262.233

合成路线

(2R,5R)-1-O-benzoyl-5,6-dihydroxy-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene

(2R,5R)-1-O-benzoyl-5,6-dihydroxy-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

(5R)-5-hydroxy-6-(tert-butyldimethylsilyloxy)-3-fluoro-1,3-dihexene

(5R)-5-hydroxy-6-(tert-butyldimethylsilyloxy)-3-fluoro-1,3-dihexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

(5R)-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-1,3-dihexene

(5R)-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-1,3-dihexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

(5R)-1,2-dihydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene

(5R)-1,2-dihydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(S)-5,6-bis-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-2-oxo-hex-3-enyl ester

Benzoic acid (E)-(S)-5,6-bis-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-2-oxo-hex-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

(5R)-1-O-benzoyl-2-hydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene

(5R)-1-O-benzoyl-2-hydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

(2R,5R)-1-O-benzoyl-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene

(2R,5R)-1-O-benzoyl-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

Benzoic acid (E)-(R)-2-ethynyl-3-fluoro-2-hydroxy-5-oxo-pent-3-enyl ester

上游原料

(5R)-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-1,3-dihexene (5R)-1,2-dihydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene (5R)-1-O-benzoyl-2-hydroxy-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-3-hexene (2R,5R)-1-O-benzoyl-5,6-dihydroxy-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene Benzoic acid (E)-(S)-5,6-bis-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-2-oxo-hex-3-enyl ester (5R)-5-hydroxy-6-(tert-butyldimethylsilyloxy)-3-fluoro-1,3-dihexene (2R,5R)-1-O-benzoyl-5,6-di(tert-butyldimethylsilyloxy)-3E-fluoro-2-hydroxy-2-ethynyl-3-hexene

下游产品

9-(5-O-benzoyl-2,3-dideoxy-2,3-didehydro-3-fluoro-4-ethynyl-β-D-furanosyl)-N6-isobutyryladenine 1-(5-O-benzoyl-2,3-dideoxy-2,3-didehydro-3-fluoro-4-ethynyl-β-D-furanosyl)thymine 1-(5-O-benzoyl-2,3-dideoxy-2,3-didehydro-3-fluoro-4-ethynyl-β-D-furanosyl)-N4-benzoylcytosine