1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

CAS号：779343-25-8

英文名：1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

分子式：C21H22FN3O3

分子量：383.416

合成路线

2,6-dichloro-α-(ethoxymethylene)-5-fluoro-β-oxo-3-pyridinepropanoic acid ethyl ester

2,6-dichloro-α-(ethoxymethylene)-5-fluoro-β-oxo-3-pyridinepropanoic acid ethyl ester

1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester

1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester

1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

1-(2,4-Dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one

上游原料

1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester 2,6-dichloro-α-(ethoxymethylene)-5-fluoro-β-oxo-3-pyridinepropanoic acid ethyl ester

下游产品

5-Chloro-3-fluoro-2-pyrrolidin-1-yl-[1,8]naphthyridine N1-(6-Fluoro-7-pyrrolidin-1-yl-[1,8]naphthyridin-4-yl)-ethane-1,2-diamine