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(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

CAS号：784156-96-3

英文名：(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

分子式：C22H32F2N2O6

分子量：458.496

合成路线

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

二碳酸二叔丁酯

二碳酸二叔丁酯

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate

Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

D-叔丁氧羰基-L-谷氨酸α苄脂

D-叔丁氧羰基-L-谷氨酸α苄脂

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

(5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

上游原料

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate 二碳酸二叔丁酯 D-叔丁氧羰基-L-谷氨酸α苄脂 Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

下游产品

(3R,6s)-3-氨基-6-(2,3-二氟苯基)-1-(2,2,2-三氟乙基)氮杂环庚烷-2-酮 2-Methyl-2-propanyl [(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-3-azepa nyl]carbamate Bis(2-methyl-2-propanyl) [(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-3- azepanyl]imidodicarbonate